Wine lovers can easily combine explorations of the fertile wine-producing regions of both Argentina from Mendoza and Chile around Santiago. These are closer than you think with a dramatic and scenic drive across the Andes between them that is in itself a great experience. Enjoy striking Andean landscapes and contrasts along the way in around 6-7 hours driving time. The highest point of the route is at 3,900 metres and the crossing is best in the warmer months from September to May. You may spot views of Mount Aconcagua, the highest peak in the Andes and head past the Mendoza River and through meandering valleys of colourful sedimentary rocks around the ancient Inca Bridge before crossing the border and descending an astonishing road of hairpin bends down towards Santiago.